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  • Evidence is increasing that all addiction without exception is related to issues with the brain's reward center, specially the mesolimbic system. This part of the problem regulates reward responses in acquiring food and sex, plus nurturing infants and children. One of the most important neurotransmitters involved in reward responses, both once they malfunction and whenever they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the amount of dopamine released in in reaction to a stimulus"(Bostwick & Bucci, 2008).

    Using two separate drugs to shed pounds can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you need to err to the side of caution and allow FDA do its job and demand some investigation be done so your public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies come in business to generate income and that they would say anything to keep people on their own medications.

    Researchers discovered that participants using this drug to get a year, dropped a few pounds within four weeks and have kept the load off throughout the 56 weeks in the study. Contrave is often a combination in the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs that are made up of many active ingredient, which might make them more efficient and safer.

    Combo-pilling could be the newest fad or in addition to this the newest to come under scrutiny and for that reason it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that using a combination of pills is now popular may be the fact that since right now there are no long term prescription weightloss pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations have been rejected or have yet to be authorized by the FDA.

    Seizures can be a side effect with Contrave and really should not be taken in those with seizure disorders. The drug also can raise blood pressure levels and heartbeat, and shouldn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure level and heart rate and must not used in patients with uncontrolled high blood pressure levels, and also by a person with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased likelihood of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

    To keep up with one of the most current articles from Wendi, the Indiana Addiction Recovery Examiner, go through the subscribe link at the top of the page to get email notification when new submissions are published. Please leave a comment for almost any article.